Lymphocyte Gene Rearrangement Studies

B-cell immunoglobulin heavy chain (IgH) gene rearrangements:
This test is for the IgH gene rearrangements (FR1, FR2 and FR3) and will detect greater than 80% of B-cell lymphoproliferative disorders.
Sample: EDTA peripheral blood or bone marrow, fresh or paraffin embedded tissue.
No Medicare rebate available.

 

Bcl-2:
This test is specific for the major breakpoint region (mbr) of the bcl-2 associated translocation [t(14;18)].
This translocation is associated with up to 85% of lymphomas with a follicular morphology, and with approximately one third of diffuse large cell lymphomas.
Sample: EDTA peripheral blood or bone marrow, fresh or paraffin embedded tissue.
No Medicare rebate available.

 

Bcl-1:
This test is specific for the translocation involving the Cyclin D1 gene [t(11;14)]. It is commonly associated with Mantle Cell Lymphoma (MCL).
Sample: EDTA peripheral blood or bone marrow, fresh or paraffin embedded tissue.
No Medicare rebate available.

 

T-cell Receptor (beta and gamma) gene rearrangements:
This test is for detecting monoclonality of T lymphocytes using primers targeted at both beta and gamma gene rearrangements, and will detect at least 90% of T-cell lymphoproliferative disorders.
Sample: EDTA peripheral blood or bone marrow, fresh or paraffin embedded tissue.
No Medicare rebate available.

 

Test Lymphocyte Gene Rearrangement Studies
Gene  
Disease  
Method  
Notes  
Specimen  
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Required Documents
(Downloadable documents are supplied within each kit dispatched)
  1. Patient Informed Consent Form: Adult
  2. Patient Informed Consent Form: Guardian
  3. Physician Test Request Form
  4. Payment Form (private patients only)
  5. Customs Declaration Form (international patients only)
  6. Import Permit Blood/DNA/Tissue (international patients only)
  7. Import Permit Buccal Swab (international patients only)
Price Please contact us here about private, public and contractual pricing arrangements
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