FAP/MAP Panel | Genomic Diagnostics

Test description

Guidelines recommend testing to confirm the diagnosis of an inherited CRC syndrome in a patient with a personal history of disease in the following circumstances:

APC gene testing is indicated in patients with ≥10 colorectal adenomas before age 30, or ≥20 colorectal adenomas regardless of age.
MUTYH gene testing is indicated for patients with ≥20 colorectal adenomas at any age, but could also be considered in patients with fewer polyps following review by a familial cancer service, and patients with an FAP phenotype but no identifiable APC variant.

Test information

Test name

FAP Gene Panel

Clinical indication

Used for investigation of FAP/MAP in patients with adenomatous polyposis where there is a familial risk of ≥10%.

Gene(s)

APC, MUTYH

Method

Massively Parallel Sequencing

Turn around time

4 weeks

Medicare eligibility

73355 – conditions apply

Price

$479 if not Medicare eligible

Test request form

Cancer Genetics Request form preferred. Standard pathology request form accepted.

Sample type

Blood x 2

Collection type

6mL EDTA

Special instructions

2 x Bloods taken at 10 minute intervals. Pre test genetic counselling required. Patient to sign consent form prior to testing.