FLT3/NPM1

Genetic markers for acute myeloid leukemia prognosis, especially with normal karyotype.

Test description

Mutations in the FLT3 and NPM1 genes are seen in acute myeloid leukaemia (particularly in cases with a normal cytogenetic karyotype) and are of prognostic significance.

Test information

Test name

Nucleophosmin & FLT3

Clinical indication

For diagnosis, prognosis, and classification in acute myeloid leukaemia

Gene(s)

NPM1, FLT3

Method

Real-time PCR analysis; Conventional PCR and capillary electrophoresis

Turn around time

2 weeks

Medicare eligibility
Price

If not MBS eligible please contact 1800 822 999 for details

Test request form

Standard pathology request form

Sample type

6mL Blood EDTA tube or 1 mL bone marrow EDTA tube

Collection type

Blood or bone marrow

Special instructions

Test is performed on either peripheral blood or bone marrow aspirate. Peripheral blood can be collected by a collector, bone marrow aspirate (doctor collect only) must be placed into EDTA.