A 31 gene panel for work up of PV, ET or PMF.
This panel combines detection of variants in JAK2, CALR and MPL with additional genes important in the diagnostic workup and prognostication of polycythaemia vera, essential thrombocythaemia and primary myelofibrosis.
Myeloproliferative Neoplasm (MPN) Panel
For diagnostic work-up of a patient with clinical and laboratory evidence of polycytheamia (PV), essential thrombocythaemia (ET) or primary myelofibrosis (PMF). Patients with suspected PMF are deemed eligible for a stem cell transplant by the requesting specialist.
ASXL1, CALR, CBL, CSF3R, CUX1, DNMT3A, ETNK1, EZH2, FLT3, GATA2, IDH1, IDH2, JAK2, JAK3, KIT, KRAS, MPL, NF1, NRAS, PTPN11, RUNX1, SETBP1, SF3B1, SH2B3, SRSF2, STAG2, STAT5B, TET2, TP53, U2AF1 and ZRSR2
Next generation sequencing
3- 4 weeks
Please call 1800 822 999 for pricing details if patient is not Medicare eligible.
Haematology genetics request form preferred. Standard pathology request form accepted.
Blood 4mL EDTA tube or Bone Marrow 4mL EDTA tube
Blood or bone marrow
Specialist/consultant physician request only
