Thrombopoietin (MPL)

Detects mutations in myeloproliferative disorders, used alongside other genetic tests.

Test description

The MPL mutations W515L and W515K are seen in a number of myeloproliferative disorders such as polycythaemia vera, essential thrombocytosis and idiopathic myelofibrosis. Consider testing in conjunction with or following other molecular tests for these disorders.

Test information

Test name

MPL (W515 mutations)

Clinical indication

To aid in the differential diagnosis and prognostic risk classification for myeloproliferative neoplasms, e.g., polycythaemia vera, essential thrombocythaemia, and primary myelofibrosis.

Gene(s)

MPL (Thrombopoietin)

Method

PCR Genotyping

Turn around time

4 weeks

Medicare eligibility

73397– criteria apply

Price

If not MBS eligible please contact 1800 822 999 for details

Test request form

Standard pathology request form

Sample type

Blood 6mL EDTA tube or Bone Marrow 4mL EDTA tube

Collection type

Blood or bone marrow

Special instructions

None